Part 2 arab board obs cholestasis thesis

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Part 2 arab board obs cholestasis thesis

Jaundice Upper right quadrant pain It is important to note that not all ICP sufferers have all of the above symptoms. For example, Jaundice only occurs in relatively small subset of cases, and in some cases abnormal lab results were not seen until 15 weeks or more after the onset of symptoms.

Mechanism[ edit ] The causes of intrahepatic cholestasis of pregnancy are still not fully understood. Twin and triplet pregnancieswhich are associated with higher hormone levels, show a higher incidence of ICP.

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Older high-dose estrogen oral contraceptive pills could cause features of ICP. It has been reported that the incidence of ICP is higher in winter than summer[ citation needed ].

Low serum selenium levels have been linked to ICP, [11] although the role of selenium in bile secretion is not known. Diagnosis[ edit ] While most pregnant women experience some itch from time to time, itching on the palms and soles without a visible rash, or persisting severe or extensive itch symptoms should be reported to the midwife or obstetrican.

The liver function tests LFTs is a simple blood test, the results of which should be available by the next day. The serum bile acid blood test for ICP is a quantitative measurement of bile salts. The results of this test often take longer to return, but the test is more specific for ICP.

Other problems with the liver that occur in pregnancy should be considered by the treating clinician. Furthermore, other causes of hepatitis, like hepatitis viruses, cancer and certain medications, should also be considered.

Treatment[ edit ] Upon diagnosis, many providers will prescribe Ursodeoxycholic Acid. While there is no cure for ICP, and no way to guarantee a successful outcome, studies have shown a slightly better fetal and maternal outcome from administration of Ursodeoxycholic Acid, whereas Cholestyramine appears to only relieve itching.

This risk rose further if bile acids doubled, [12] Risks if untreated[ edit ] Maternal consequences include the following: Itching, which can become intense and debilitating Premature labor Deranged clotting, which requires Vitamin K Fetal consequences include:initiativeblog.com is a platform for academics to share research papers.

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Part 2 arab board obs cholestasis thesis

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