Share - The final analysis at 18 months of the patient Phase II clinical study in early Alzheimer's disease demonstrated statistically significant slowing in clinical decline and reduction of amyloid beta accumulated in the brain - First late-stage study data successfully demonstrating potential disease-modifying effects on both clinical function and amyloid beta accumulation in the brain - New data provide compelling evidence to further support amyloid hypothesis as a therapeutic target for Alzheimer's disease TOKYO and CAMBRIDGE, Mass.
Features[ edit ] DVD Shrink is designed to be easy to use. It is contained within a single executable file that is one megabyte in size. The program features a DeCSS decryption algorithmenabling it to open and decrypt many currently available DVDs, although it is defeated by some newer copy protection techniques.
The user is able to choose how the compression is to be distributed across the DVD. The transcoder in DVD Shrink was unusual at the time of its release in that it employs compressed domain video processing technology to avoid a full decode and re-encode of the video stream.
This boosts performance significantly as only part of the video stream is decoded and scraped. In "Reauthor" mode, the interface allows the user to choose specifically which DVD elements Main Title, Menus, audio tracks and subtitles, and Special Features to retain on the "shrunken" DVD; the Menu clips are stored in folders and some of them are playable.
The compression is automatic if the Main Title only is selected, to fit it onto the selected size of DVD.
If Special Features are also selected, their compression may be manually selected at the minimum possible using the Custom Ratio option, to give disk space to the Main Title. The compression can be automatic or manual, which allows selection of greatest compression for Menus or Special Features, saving disc space for the Main Title.
In either mode, the program has options to facilitate the stripping of the CSS copy protectionUser operation prohibition prohibiting skipping over previews or " FBI Warnings" and so onand also allows the copy to be either made region-free the default setting or set for any region code.
DVD Shrink can also shrink hard disk files already ripped by programs that can overcome more recent copy protection systems, but that do not offer the 2-layer to 1-layer compression. The program cannot burn these images itself, as it does not contain a built-in burning engine.
This process appears transparent to the end user. To burn with ImgBurn it's possible to either copy over imgburn. Although DVD Shrink gives the user free rein over compression settings for individual tracks on the DVD, removing content altogether is not allowed as there is a risk of upsetting the DVD's menu software.
Audio tracks and subtitles can, however, be removed.
DVD Shrink also gives the alternative option of transferring selected sections as a series of stills, which acts as a high-compression "placeholder" for the original. Recent events increase in processor speed, lower cost terabyte disk storage, RAID drive functionality, etc.
DVD Shrink has other, less controversial uses. In particular, the 8-cm discs produced by the new DVD-based video camcorders are not fully compatible with all computers and DVD players; "ripping" them with DVD Shrink or a similar program and re-recording them to standard-sized DVDs is a quick and very effective solution to this problem.
It also allows the recorded footage to be used with drives that do not support 8-cm discs, such as slot-loading drives often used in Apple Macintosh computers.
DVD Shrink is now available from the official web page again, as it is available from many other sites on the Internet as well, and it suggests finding a download source using a general web search, "DVD Shrink".
In some countries, the software in itself is illegal under applicable laws pertaining to copyrighted content. German law, for instance, while allowing the manufacture of copies of copyrighted digital material for personal, non-commercial use, dictates that it is illegal to circumvent mechanisms that prevent copying.
Therefore, the use of any software enabling a user to work around copyright restrictions such as CSS is against the law in Germany. Recently, the software has moved to donationware through the Sellfy platform.
Alternate sites like Softpedia have been providing a clean, adware-free download of DVDShrink for a decade too. Another copy of the checksums of DVD Shrink is stored at the doom9 forum.Tariffs revision designed to cure trade deficits have become a live and contentious economic policy issue.
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He was the founding president of the Canadian Auto Workers union – now known as Unifor, the largest private-sector union in Canada – and a former president of the Canadian Labour Congress, the national federation of Canadian unions.
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Watch video · Analysis Interpretation of the news based on evidence, including data, The video racked up more than 30 million views on YouTube in 48 hours, and sleuths among those viewers have taken to. Mar 08, · Final Offer Analysis The movie that we watched in class had the most impact on me in from everything I have learned in this class yet.
Many different aspects showed me the different aspects and techniques used to win a negotiation under large amounts of pressure.